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Owen11Parameters Struct Reference

#include <Owen11Parameters.hpp>

+ Collaboration diagram for Owen11Parameters:

Static Public Attributes

static const boost::shared_ptr< ParameterInstance< unit::pressure > > mpInletPressure
 
static const boost::shared_ptr< ParameterInstance< unit::pressure > > mpOutletPressure
 
static const boost::shared_ptr< ParameterInstance< unit::dynamic_viscosity > > mpPlasmaViscosity
 
static const boost::shared_ptr< ParameterInstance< unit::time > > mpMinimumCellCyclePeriodNormal
 
static const boost::shared_ptr< ParameterInstance< unit::time > > mpMinimumCellCyclePeriodCancer
 
static const boost::shared_ptr< ParameterInstance< unit::time > > mpTimeToDeathDueToQuiescence
 
static const boost::shared_ptr< ParameterInstance< unit::pressure > > mpOxygenPartialPressureAtHalfMaxCycleRateNormal
 
static const boost::shared_ptr< ParameterInstance< unit::pressure > > mpOxygenPartialPressureAtHalfMaxCycleRateCancer
 
static const boost::shared_ptr< ParameterInstance< unit::pressure > > mpOxygenPartialPressureAtQuiescence
 
static const boost::shared_ptr< ParameterInstance< unit::pressure > > mpOxygenPartialPressureLeaveQuiescence
 
static const boost::shared_ptr< ParameterInstance< unit::diffusivity_per_concentration > > mpChemotacticSensitivity
 
static const boost::shared_ptr< ParameterInstance< unit::diffusivity > > mpCellMotilityNormal
 
static const boost::shared_ptr< ParameterInstance< unit::diffusivity > > mpCellMotilityCancer
 
static const boost::shared_ptr< ParameterInstance< unit::diffusivity > > mpCellMotilityEndothelial
 
static const boost::shared_ptr< ParameterInstance< unit::membrane_permeability > > mpVesselOxygenPermeability
 
static const boost::shared_ptr< ParameterInstance< unit::membrane_permeability > > mpVesselVegfPermeability
 
static const boost::shared_ptr< ParameterInstance< unit::rate > > mpCellOxygenConsumptionRate
 
static const boost::shared_ptr< ParameterInstance< unit::concentration_flow_rate > > mpCellVegfSecretionRate
 
static const boost::shared_ptr< ParameterInstance< unit::rate > > mpMaximumSproutingRate
 
static const boost::shared_ptr< ParameterInstance< unit::concentration > > mpVegfConventrationAtHalfMaxProbSprouting
 
static const boost::shared_ptr< ParameterInstance< unit::length > > mpSproutingExclusionRadius
 
static const boost::shared_ptr< ParameterInstance< unit::time > > mpMaxTimeWithLowWallShearStress
 
static const boost::shared_ptr< ParameterInstance< unit::pressure > > mpCriticalWallShearStress
 
static const boost::shared_ptr< ParameterInstance< unit::time > > mpMasterStepTime
 
static const boost::shared_ptr< ParameterInstance< unit::time > > mpSimulationDuration
 
static const boost::shared_ptr< ParameterInstance< unit::length > > mpLatticeSpacing
 
static const boost::shared_ptr< ParameterInstance< unit::diffusivity > > mpOxygenDiffusivity
 
static const boost::shared_ptr< ParameterInstance< unit::diffusivity > > mpVegfDiffusivity
 
static const boost::shared_ptr< ParameterInstance< unit::rate > > mpVegfDecayRate
 
static const boost::shared_ptr< ParameterInstance< unit::dimensionless > > mpInflowHaematocrit
 
static const boost::shared_ptr< ParameterInstance< unit::rate > > mpP53ProductionRateConstant
 
static const boost::shared_ptr< ParameterInstance< unit::rate > > mpP53MaxDegradationRate
 
static const boost::shared_ptr< ParameterInstance< unit::pressure > > mpOxygenTensionForHalfMaxP53Degradation
 
static const boost::shared_ptr< ParameterInstance< unit::rate > > mpCellVegfProductionRate
 
static const boost::shared_ptr< ParameterInstance< unit::rate > > mpMaxCellVegfProductionRate
 
static const boost::shared_ptr< ParameterInstance< unit::rate > > mpP53EffectOnVegfProduction
 
static const boost::shared_ptr< ParameterInstance< unit::dimensionless > > mpVegfEffectOnVegfProduction
 
static const boost::shared_ptr< ParameterInstance< unit::pressure > > mpOxygenTensionForHalfMaxVegfDegradation
 
static const boost::shared_ptr< ParameterInstance< unit::time > > mpVesselRadiusUpdateTimestep
 
static const boost::shared_ptr< ParameterInstance< unit::length > > mpMinimumRadius
 
static const boost::shared_ptr< ParameterInstance< unit::length > > mpMaximumRadius
 
static const boost::shared_ptr< ParameterInstance< unit::flow_rate > > mpReferenceFlowRateForMetabolicStimulus
 
static const boost::shared_ptr< ParameterInstance< unit::rate > > mpShrinkingTendency
 
static const boost::shared_ptr< ParameterInstance< unit::rate > > mpSensitivityToIntravascularPressure
 
static const boost::shared_ptr< ParameterInstance< unit::rate > > mpBasalMetabolicStimulus
 
static const boost::shared_ptr< ParameterInstance< unit::pressure > > mpReferencePartialPressure
 

Detailed Description

This struct stores parameter values used in the paper Owen et al. (2011)

Definition at line 46 of file Owen11Parameters.hpp.

Member Data Documentation

const boost::shared_ptr< ParameterInstance< unit::rate > > Owen11Parameters::mpBasalMetabolicStimulus
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::rate> >(new ParameterInstance<unit::rate> (1.7/unit::seconds,
"Owen11_BasalMetabolicStimulus",
"Basal metabolic stimulus",
"k^0_m",
bib_info))

Basal metabolic stimulus k^0_m

Definition at line 276 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::diffusivity > > Owen11Parameters::mpCellMotilityCancer
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::diffusivity> >(new ParameterInstance<unit::diffusivity> (0.5*micron_sq/min,
"Owen11_CellMotilityCancer",
"Maximum cell motility cancer",
"D_{cancer}",
bib_info))

Maximum cell motility D_{cancer}

Definition at line 111 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::diffusivity > > Owen11Parameters::mpCellMotilityEndothelial
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::diffusivity> >(new ParameterInstance<unit::diffusivity> (1.0*micron_sq/min,
"Owen11_CellMotilityEndothelial",
"Maximum cell motility endothelial",
"D_{endo}",
bib_info))

Maximum cell motility D_{endo}

Definition at line 116 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::diffusivity > > Owen11Parameters::mpCellMotilityNormal
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::diffusivity> >(new ParameterInstance<unit::diffusivity> (0.0*micron_sq/min,
"Owen11_CellMotilityNormal",
"Maximum cell motility normal",
"D_{normal}",
bib_info))

Maximum cell motility D_{normal}

Definition at line 106 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::rate > > Owen11Parameters::mpCellOxygenConsumptionRate
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::rate> >(new ParameterInstance<unit::rate> (13.0/min,
"Owen11_CellOxygenConsumptionRate",
"Cell oxygen consumption rate",
"k_c^{cell}",
bib_info))

Cell oxygen consumption rate ^{cell}

Definition at line 136 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::rate > > Owen11Parameters::mpCellVegfProductionRate
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::rate> >(new ParameterInstance<unit::rate> (0.002/min,
"Owen11_CellVegfProductionRate",
"Basal VEGF production rate in cell",
"k_8",
bib_info))

Basal VEGF production rate in cell k_8

Definition at line 221 of file Owen11Parameters.hpp.

Referenced by Owen2011OxygenBasedCellCycleOdeSystem::Owen2011OxygenBasedCellCycleOdeSystem().

const boost::shared_ptr< ParameterInstance< unit::concentration_flow_rate > > Owen11Parameters::mpCellVegfSecretionRate
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::concentration_flow_rate> >(new ParameterInstance<unit::concentration_flow_rate> (0.01*nano_molar/min,
"Owen11_CellVegfSecretionRate",
"Cell vegf secretion rate",
"k_v^{cell}",
bib_info))

Cell vegf secretion rate ^{cell}

Definition at line 141 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::diffusivity_per_concentration > > Owen11Parameters::mpChemotacticSensitivity
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::diffusivity_per_concentration> >(new ParameterInstance<unit::diffusivity_per_concentration> (chemotactic_sensitivty,
"Owen11_ChemotacticSensitivity",
"Chemotactic sensitivity",
"\\Chi",
bib_info))

Chemotactic sensitivity

Definition at line 101 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::pressure > > Owen11Parameters::mpCriticalWallShearStress
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::pressure> >(new ParameterInstance<unit::pressure> (8.0 * dyne/(cm*cm),
"Owen11_CriticalWallShearStress",
"Critical wall shear stress for vessel pruning",
"\\tau_{wall}",
bib_info))

Critical wall shear stress for vessel pruning {wall}

Definition at line 166 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::dimensionless > > Owen11Parameters::mpInflowHaematocrit
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::dimensionless> >(new ParameterInstance<unit::dimensionless> (0.45,
"Owen11_InflowHaematocrit",
"Inflow haematocrit",
"H_{in}",
bib_info))

Inflow haematocrit H_{in}

Definition at line 201 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::pressure > > Owen11Parameters::mpInletPressure
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::pressure> >(new ParameterInstance<unit::pressure> (inlet_pressure,
"Owen11_InletPressure",
"Vessel network inlet pressure$",
"P_{in}",
bib_info))

Network Inlet Pressure: P_in

Definition at line 51 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::length > > Owen11Parameters::mpLatticeSpacing
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::length> >(new ParameterInstance<unit::length> (40.0*um,
"Owen11_LatticeSpacing",
"Lattice spacing",
"\\Delta x",
bib_info))

Lattice spacing x

Definition at line 181 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::time > > Owen11Parameters::mpMasterStepTime
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::time> >(new ParameterInstance<unit::time> (30.0 * min,
"Owen11_MasterStepTime",
"Master step time",
"\\Delta t",
bib_info))

Master step time t

Definition at line 171 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::rate > > Owen11Parameters::mpMaxCellVegfProductionRate
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::rate> >(new ParameterInstance<unit::rate> (0.01/min,
"Owen11_MaxCellVegfProductionRate",
"Max VEGF production rate in cell",
"k_8_dash",
bib_info))

Max VEGF production rate in cell k_8_dash

Definition at line 226 of file Owen11Parameters.hpp.

Referenced by Owen2011OxygenBasedCellCycleOdeSystem::Owen2011OxygenBasedCellCycleOdeSystem().

const boost::shared_ptr< ParameterInstance< unit::length > > Owen11Parameters::mpMaximumRadius
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::length> >(new ParameterInstance<unit::length> (50.e-6*unit::metres,
"Owen11_MaximumRadius",
"Maximum possible radius",
"R_{MAX}",
bib_info))

Maximum possible radius R_{MAX}

Definition at line 256 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::rate > > Owen11Parameters::mpMaximumSproutingRate
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::rate> >(new ParameterInstance<unit::rate> (0.00025/min,
"Owen11_MaximumSproutingRate",
"Maximum rate of sprouting",
"P^{max}_{sprout}",
bib_info))

Maximum rate of sprouting P^{max}_{sprout}

Definition at line 146 of file Owen11Parameters.hpp.

Referenced by OffLatticeSproutingRule< DIM >::OffLatticeSproutingRule(), and Owen2011SproutingRule< DIM >::Owen2011SproutingRule().

const boost::shared_ptr< ParameterInstance< unit::time > > Owen11Parameters::mpMaxTimeWithLowWallShearStress
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::time> >(new ParameterInstance<unit::time> (4000.0 * min,
"Owen11_MaxTimeWithLowWallShearStress",
"Maximum vessel survivial time with low wall shear stress",
"T_{prune}",
bib_info))

Maximum vessel survivial time with low wall shear stress T_{prune}

Definition at line 161 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::time > > Owen11Parameters::mpMinimumCellCyclePeriodCancer
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::time> >(new ParameterInstance<unit::time> (1600.0*min,
"Owen11_MinCellCycleCancer",
"Minimum cell cycle period cancer",
"T_{min}_{cancer}",
bib_info))

Minimum cell cycle period T_{min}_{cancer}

Definition at line 71 of file Owen11Parameters.hpp.

Referenced by Owen2011OxygenBasedCellCycleOdeSystem::Owen2011OxygenBasedCellCycleOdeSystem().

const boost::shared_ptr< ParameterInstance< unit::time > > Owen11Parameters::mpMinimumCellCyclePeriodNormal
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::time> >(new ParameterInstance<unit::time> (3000.0*min,
"Owen11_MinCellCycleNormal",
"Minimum cell cycle period normal",
"T_{min}_{normal}",
bib_info))

Minimum cell cycle period T_{min}_{normal}

Definition at line 66 of file Owen11Parameters.hpp.

Referenced by Owen2011OxygenBasedCellCycleOdeSystem::Owen2011OxygenBasedCellCycleOdeSystem().

const boost::shared_ptr< ParameterInstance< unit::length > > Owen11Parameters::mpMinimumRadius
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::length> >(new ParameterInstance<unit::length> (1.e-6*unit::metres,
"Owen11_MinimumRadius",
"Minimum possible radius",
"R_{MIN}",
bib_info))

Minimum possible radius R_{MIN}

Definition at line 251 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::pressure > > Owen11Parameters::mpOutletPressure
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::pressure> >(new ParameterInstance<unit::pressure> (outlet_pressure,
"Owen11_OutletPressure",
"Vessel network outlet pressure",
"P_{out}",
bib_info))

Network Outlet Pressure: P_out

Definition at line 56 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::diffusivity > > Owen11Parameters::mpOxygenDiffusivity
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::diffusivity> >(new ParameterInstance<unit::diffusivity> (0.00145*cm*cm/min,
"Owen11_OxygenDiffusivity",
"Oxygen diffusivity ",
"D_{c}",
bib_info))

Oxygen diffusivity D_{c}

Definition at line 186 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::pressure > > Owen11Parameters::mpOxygenPartialPressureAtHalfMaxCycleRateCancer
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::pressure> >(new ParameterInstance<unit::pressure> (1.4*mmHg,
"Owen11_OxygenAtHalfMaxCycleRateCancer",
"Oxygen partial pressure at half max cell cycle rate cancer",
"C_{\\phi}_{cancer}",
bib_info))

Oxygen partial pressure at half max cell cycle rate C_{}_{cancer}

Definition at line 86 of file Owen11Parameters.hpp.

Referenced by Owen2011OxygenBasedCellCycleOdeSystem::Owen2011OxygenBasedCellCycleOdeSystem().

const boost::shared_ptr< ParameterInstance< unit::pressure > > Owen11Parameters::mpOxygenPartialPressureAtHalfMaxCycleRateNormal
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::pressure> >(new ParameterInstance<unit::pressure> (3.0*mmHg,
"Owen11_OxygenAtHalfMaxCycleRateNormal",
"Oxygen partial pressure at half max cell cycle rate normal",
"C_{\\phi}_{normal}",
bib_info))

Oxygen partial pressure at half max cell cycle rate C_{}_{normal}

Definition at line 81 of file Owen11Parameters.hpp.

Referenced by Owen2011OxygenBasedCellCycleOdeSystem::Owen2011OxygenBasedCellCycleOdeSystem().

const boost::shared_ptr< ParameterInstance< unit::pressure > > Owen11Parameters::mpOxygenPartialPressureAtQuiescence
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::pressure> >(new ParameterInstance<unit::pressure> (8.9*mmHg,
"Owen11_OxygenAtQuiescence",
"Oxygen partial pressure at quiescence",
"C^{enter}_{quiesc}",
bib_info))

Oxygen partial pressure at quiescence C^{enter}_{quiesc}

Definition at line 91 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::pressure > > Owen11Parameters::mpOxygenPartialPressureLeaveQuiescence
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::pressure> >(new ParameterInstance<unit::pressure> (9.8*mmHg,
"Owen11_OxygenLeaveQuiescence",
"Oxygen partial pressure to leave quiescence",
"C^{leave}_{quiesc}",
bib_info))

Oxygen partial pressure to leave quiescence C^{leave}_{quiesc}

Definition at line 96 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::pressure > > Owen11Parameters::mpOxygenTensionForHalfMaxP53Degradation
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::pressure> >(new ParameterInstance<unit::pressure> (4.44*mmHg,
"Owen11_OxygenTensionForHalfMaxP53Degradation",
"Tissue oxygen tension for half-max p53 degradation",
"C_{p53}",
bib_info))

Tissue oxygen tension for half-max p53 degradation C_{p53}

Definition at line 216 of file Owen11Parameters.hpp.

Referenced by Owen2011OxygenBasedCellCycleOdeSystem::Owen2011OxygenBasedCellCycleOdeSystem().

const boost::shared_ptr< ParameterInstance< unit::pressure > > Owen11Parameters::mpOxygenTensionForHalfMaxVegfDegradation
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::pressure> >(new ParameterInstance<unit::pressure> (4.44*mmHg,
"Owen11_OxygenTensionForHalfMaxVegfDegradation",
"Tissue oxygen tension for half-max vegf degradation",
"C_{VEGF}",
bib_info))

Tissue oxygen tension for half-max vegf degradation C_{VEGF}

Definition at line 241 of file Owen11Parameters.hpp.

Referenced by Owen2011OxygenBasedCellCycleOdeSystem::Owen2011OxygenBasedCellCycleOdeSystem().

const boost::shared_ptr< ParameterInstance< unit::rate > > Owen11Parameters::mpP53EffectOnVegfProduction
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::rate> >(new ParameterInstance<unit::rate> (-0.002/min,
"Owen11_P53EffectOnVegfProduction",
"Effect of P53 on VEGF production",
"k_8_dash_dash",
bib_info))

Effect of P53 on vegf production k_8_dash_dash

Definition at line 231 of file Owen11Parameters.hpp.

Referenced by Owen2011OxygenBasedCellCycleOdeSystem::Owen2011OxygenBasedCellCycleOdeSystem().

const boost::shared_ptr< ParameterInstance< unit::rate > > Owen11Parameters::mpP53MaxDegradationRate
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::rate> >(new ParameterInstance<unit::rate> (0.01/min,
"Owen11_P53MaxDegradationRate",
"Max p53 degradation rate",
"k_dash_7",
bib_info))

Max p53 degradation rate k_dash_7

Definition at line 211 of file Owen11Parameters.hpp.

Referenced by Owen2011OxygenBasedCellCycleOdeSystem::Owen2011OxygenBasedCellCycleOdeSystem().

const boost::shared_ptr< ParameterInstance< unit::rate > > Owen11Parameters::mpP53ProductionRateConstant
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::rate> >(new ParameterInstance<unit::rate> (0.002/min,
"Owen11_P53ProductionRateConstant",
"Intracellular p53 production rate constant",
"k_7",
bib_info))

Intracellular p53 production rate constant k_7

Definition at line 206 of file Owen11Parameters.hpp.

Referenced by Owen2011OxygenBasedCellCycleOdeSystem::Owen2011OxygenBasedCellCycleOdeSystem().

const boost::shared_ptr< ParameterInstance< unit::dynamic_viscosity > > Owen11Parameters::mpPlasmaViscosity
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::dynamic_viscosity> >(new ParameterInstance<unit::dynamic_viscosity> (plasma_visocity,
"Owen11_PlasmaViscosity",
"Blood plasma viscosity",
"\\mu_{plasma}",
bib_info))

Plasma viscosity {plasma}

Definition at line 61 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::flow_rate > > Owen11Parameters::mpReferenceFlowRateForMetabolicStimulus
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::flow_rate> >(new ParameterInstance<unit::flow_rate> (4.e-5*cm*cm*cm/min,
"Owen11_ReferenceFlowRateForMetabolicStimulus",
"Reference flow rate for metabolic stimulus",
"Q_{ref}",
bib_info))

Reference flow rate for metabolic stimulus Q_{ref}

Definition at line 261 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::pressure > > Owen11Parameters::mpReferencePartialPressure
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::pressure> >(new ParameterInstance<unit::pressure> (20.0*mmHg,
"Owen11_ReferencePartialPressure",
"Reference partial pressure of inlet haematocrit vessels",
"C_{Ref}",
bib_info))

Reference partial pressure of inlet haematocrit vessels C_{Ref}

Definition at line 281 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::rate > > Owen11Parameters::mpSensitivityToIntravascularPressure
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::rate> >(new ParameterInstance<unit::rate> (0.5/unit::seconds,
"Owen11_SensitivityToIntravascularPressure",
"Shrinking to intravascaulr pressure",
"k_p",
bib_info))

Shrinking to intravascaulr pressure k_p

Definition at line 271 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::rate > > Owen11Parameters::mpShrinkingTendency
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::rate> >(new ParameterInstance<unit::rate> (1.7/unit::seconds,
"Owen11_ShrinkingTendency",
"Shrinking tendency",
"k_s",
bib_info))

Shrinking tendency k_s

Definition at line 266 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::time > > Owen11Parameters::mpSimulationDuration
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::time> >(new ParameterInstance<unit::time> (200.0 * day,
"Owen11_SimulationDuration",
"Simulation duration",
"T_{final}",
bib_info))

Simulation duration T_{final}

Definition at line 176 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::length > > Owen11Parameters::mpSproutingExclusionRadius
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::length> >(new ParameterInstance<unit::length> (80.0 * um,
"Owen11_SproutingExclusionRadius",
"Sprouting exclusion radius",
"R_{ex}",
bib_info))

Sprouting exclusion radius (R_{ex})

Definition at line 156 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::time > > Owen11Parameters::mpTimeToDeathDueToQuiescence
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::time> >(new ParameterInstance<unit::time> (4000.0*min,
"Owen11_TimeDeathQuiescence",
"Time for death due to sustained quiescence",
"T_{death}",
bib_info))

Time for death due to sustained quiescence T_{death}

Definition at line 76 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::concentration > > Owen11Parameters::mpVegfConventrationAtHalfMaxProbSprouting
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::concentration> >(new ParameterInstance<unit::concentration> (0.5*nano_molar,
"Owen11_VegfConventrationAtHalfMaxProbSprouting",
"VEGF concentration at half maximal vessel sprouting probability",
"V_{sprout}",
bib_info))

VEGF concentration at half maximal vessel sprouting probability V_{sprout}

Definition at line 151 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::rate > > Owen11Parameters::mpVegfDecayRate
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::rate> >(new ParameterInstance<unit::rate> (0.01/min,
"Owen11_VegfDecayRate",
"Vegf decay rate ",
"\\delta_{v}",
bib_info))

Vegf decay rate {v}

Definition at line 196 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::diffusivity > > Owen11Parameters::mpVegfDiffusivity
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::diffusivity> >(new ParameterInstance<unit::diffusivity> (1.e-5*cm*cm/min,
"Owen11_VegfDiffusivity",
"Vegf diffusivity ",
"D_{v}",
bib_info))

Vegf diffusivity D_{v}

Definition at line 191 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::dimensionless > > Owen11Parameters::mpVegfEffectOnVegfProduction
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::dimensionless> >(new ParameterInstance<unit::dimensionless> (0.04,
"Owen11_VegfEffectOnVegfProduction",
"Effect of VEGF on VEGF production",
"j_5",
bib_info))

Effect of VEGF on VEGF production j_5

Definition at line 236 of file Owen11Parameters.hpp.

Referenced by Owen2011OxygenBasedCellCycleOdeSystem::Owen2011OxygenBasedCellCycleOdeSystem().

const boost::shared_ptr< ParameterInstance< unit::membrane_permeability > > Owen11Parameters::mpVesselOxygenPermeability
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::membrane_permeability> >(new ParameterInstance<unit::membrane_permeability> (6.0*cm/min,
"Owen11_VesselOxygenPermeability",
"Vessel permeability to oxygen",
"\\psi_{c}",
bib_info))

p53 concentration for apoptosis p53_{THR} Vessel permeability to oxygen {c}

Definition at line 126 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::time > > Owen11Parameters::mpVesselRadiusUpdateTimestep
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::time> >(new ParameterInstance<unit::time> (0.1*unit::seconds,
"Owen11_VesselRadiusUpdateTimestep",
"Vessel radius update timestep",
"\\epsilon_t",
bib_info))

Vessel radius update timestep

Definition at line 246 of file Owen11Parameters.hpp.

const boost::shared_ptr< ParameterInstance< unit::membrane_permeability > > Owen11Parameters::mpVesselVegfPermeability
static
Initial value:
=
boost::shared_ptr<ParameterInstance<unit::membrane_permeability> >(new ParameterInstance<unit::membrane_permeability> (1.e-5*cm/min,
"Owen11_VesselVegfPermeability",
"Vessel permeability to vegf",
"\\psi_{v}",
bib_info))

Vessel permeability to vegf {v}

Definition at line 131 of file Owen11Parameters.hpp.

The documentation for this struct was generated from the following files: